St. Cloud is home crew base for Empire Builder operating crews, who work east to Winona, Minnesota and west to Minot, North Dakota.
St. Cloud is the county seat of Stearns County, Minnesota. Most of the city of St. Cloud is in Stearns County, west of the Mississippi River. Areas of St. Cloud east of the Mississippi River are in Benton and Foley counties. The St. Cloud Amtrak station is located in Benton County.
The St. Cloud area is home to numerous institutes of higher learning, including St. Cloud State University, the St. Cloud Technical and Community College, the College of St. Benedict (in St. Joseph), and St. John's University (in Collegeville).